Media Summary: Practical considerations of using CRISPR-Cas9 such as off-target effects, and various applications besides Brief introduction into the problem of identifying causal variants, from association signals detected in GWAS. Introduction to CRISPR-Cas9, guide RNAs (single and dual), PAM sites.
2022 Mcb 182 Lecture 9 Human Genetics - Detailed Analysis & Overview
Practical considerations of using CRISPR-Cas9 such as off-target effects, and various applications besides Brief introduction into the problem of identifying causal variants, from association signals detected in GWAS. Introduction to CRISPR-Cas9, guide RNAs (single and dual), PAM sites. Introduction to the inference of chromatin states from epigenetic data Introduction to the concept of absolute entropy and information content of DNA sequences Introduction to the chromatin conformation capture assays, including 3C and 4C.
